
DNA-PKcs Dysfunction Enhances the Antitumor Activity of Radioimmunotherapy by Activating the cGAS-STING Pathway in HNSCC
Introduction Head and neck squamous cell carcinoma (HNSCC) is a prevalent cancer worldwide. In the US, approximately 55,000 new cases and 12,000 deaths from HNSCC are expected by 2023.1 HNSCC responds well to radiotherapy (RT), making it an effective …